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zardavérine

zardaverine

santé / chimie - iate.europa.eu

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Crystal structure of phosphodiesterase 4d and inhibitor complex11atomic coordinates (code 1mkd) have been deposited in the protein data bank. ... The first crystal structure of PDE4D catalytic domain and a bound inhibitor, zardaverine, was determined....

général - core.ac.uk -

Effects of the mixed phosphodiesterase iii/iv inhibitor, zardaverine, on airway function in patients with chronic airflow obstruction AbstractZardaverine is a selective inhibitor of phosphodiesterase (PDE) III and IV isozymes....

The selective antitumor activity of zardaverine is closely related to the regulation of cell cycle-associated proteins.Bel-7402 and SMMC-7721 cells (A), SNU-739 and HCT 116 cells (B) were incubated with zardaverine for 24 h....

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Zardaverine causes g0/g1 phase cell cycle arrest of sensitive cells....0.1 µM zardaverine or vehicle for 24 h, then collected, stained with PI, and analyzed by flow cytometry....

PDF: figshare.com

Zardaverine dose- and time-dependently induces apoptosis.A, Bel-7402 and SMMC-7721 cells were incubated with zardaverine for 48 h....

PDF: figshare.com

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