The structure of methylated xanthines in relation to their effects on dna synthesis and cell lethality in nitrogen mustard-treated cells.... A correlation is observed between the ability of these xanthines to reverse the inhibitory effects of nitrogen mustard damage on DNA synthesis and their ability to enhance nitrogen mustard lethality in human HT-29 cells...
Down-regulation of her-2 expression in human breast cancer cell hbc-4 and zr75-1 by nitrogen-mustard-n-oxideBackground and Aims: The human epidermal growth factor receptor type 2(HER-2) seems to be sensitive to nitrogen mustard, because nitrogen mustard heavilyalkylates on guanine...
Excision repair of nitrogen mustard-dna adducts in saccharomyces cerevisiae.The bifunctional alkylating anticancer drug nitrogen mustard forms a variety of DNA lesions, including monoadducts and intrastrand and interstrand crosslinks...
X-rays and nitrogen mustard independent action in chinese hamster cellsWe have studied the combined effects of X-irradiation and nitrogen mustard treatment on the colony-forming ability of Chinese hamster cells...