Also provided are the process for preparing anhydrous voglibose from said half-hydrated crystal of voglibose and the use of said half-hydrated crystal of voglibose in the pharmaceutical preparation for curing diabetes.

Disclosed is the compound valiolone, which has formula (I), a method of preparing valiolone, and a method of using valiolone to prepare acarbose and voglibose.

One trial each compared voglibose with placebo (1780 participants) or diet and exercise (870 participants).

This issue has been significantly addressed by voglibose which brought about a 40% reduction in progression to diabetes over one year.

The highly purified valiolamine prepared by a method of the invention can be used for making highly purified voglibose which is medicament for treating diabetes.

Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.

Also provided are processes for the purification of substituted or unsubstituted 5-oxo-1,2,3,4-cyclohexanetetrol and substituted 5-amino-1,2,3,4-cyclohexanetetrol, which compounds are useful intermediates in the preparation of voglibose.

We found 10 randomised controlled trials representing 11,814 participants, eight investigating acarbose and two investigating voglibose.

The present invention relates to pharmaceutical sustained release formulations of α-glucosidase inhibitors as for example acarbose, miglitol, emiglitate or voglibose leading to a reduction of side effects.

Voglinorm, an alpha-glucosidase inhibitor, is a synthetic compound with potent and enduring therapeutic efficacies against disorders of sensory, motor and autonomic nerve systems due to diabetes mellitus.

For all other reported outcome measures there were no clear differences between voglibose and comparator groups.

Voglibose, an alpha-glucosidase inhibitor, is a synthetic compound with potent and enduring therapeutic efficacies against disorders of sensory, motor and autonomic nerve systems due to diabetes mellitus. ...

Voglibose, an alpha-glucosidase inhibitor, is a synthetic compound with potent and enduring therapeutic efficacies against disorders of sensory, motor and autonomic nerve systems due to diabetes mellitus.

In a further study, linagliptin monotherapy showed superiority in glucose lowering versus placebo and versus voglibose, the most commonly used alpha glucosidase inhibitor in Japan.5-6