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vapiprost

santé / chimie - iate.europa.eu
Pharmacological characterization of thromboxane and prostanoid receptors in human isolated urinary bladder... The selective TXA(2) antagonist, GR 32191B (vapiprost), antagonized U-46619-induced contractions with an apparent pK(B) value of 8.27±0.12...
santé / détérioration de l'environnement / produit animal - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Publications scientifiques

The pharmacodynamics and pharmacokinetics of a novel thromboxane receptor blocking drug vapiprost (gr32191) after single intravenous doses in healthy subjects.1 The effect of single, serially increasing, intravenous doses of a specific thromboxane receptor blocking drug, vapiprost, upon platelet aggregation induced ex vivo by the thromboxane A2 mimetic, U-46619, was examined in 12 healthy males....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Effects of vapiprost, a novel thromboxane receptor antagonist, on thrombus formation and vascular patency after thrombolysis by tissue-type plasminogen activator.... Pretreatment with vapiprost (0.1,...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Comparative antiplatelet effects of aspirin, vapiprost and gr144053, a gpiib/iiia antagonist, with a special reference to the role of platelet microaggregates... We adopted this device to comparatively evaluate the inhibitory effects of aspirin (1, 3 or 10 mg kg(−1)), vapiprost (0.3,...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Involvement of nitric oxide and eicosanoids in platelet-activating factor-induced haemodynamic and haematological effects in dogs.... The thromboxane A2/prostaglandin H2 (TP)-receptor antagonist vapiprost blocked the PAF-induced rise in pulmonary vascular resistance....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov


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