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Quantitative analysis linking inner hair cell voltage changes and postsynaptic conductance change: a modelling study... A generic and tunable topology of the mammalian synaptic ribbon is generated and the voltage dependence of its substructures is used to calculate discrete and probabilistic neurotransmitter vesicle release....
général - core.ac.uk - PDF: doaj.org
Aczonin, a 550-kd putative scaffolding protein of presynaptic active zones, shares homology regions with rim and bassoon and binds profilin... We propose that aczonin is a scaffolding protein involved in the organization of the molecular architecture of synaptic active zones and in the orchestration of neurotransmitter vesicle trafficking
Short term synaptic depression imposes a frequency dependent filter on synaptic information transferDepletion of synaptic neurotransmitter vesicles induces a form of short term depression in synapses throughout the nervous system....
B: short term synaptic depression imposes a frequency dependent filter on synaptic information transferDepletion of synaptic neurotransmitter vesicles induces a form of short term depression in synapses throughout the nervous system....
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Cellular and subcellular localization of protein i in the peripheral nervous system.... Protein I was found to be enriched in neurotransmitter vesicle fractions of peripheral nervous tissue....
santé - iate.europa.eu
Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins... We performed this here for synaptic proteins, in a protocol that we termed comparative synaptosome imaging for semi-quantitative copy numbers (CosiQuant)....
général - core.ac.uk - PDF: doaj.org
Neuroleptic drug-stimulated iron uptake by synaptosome preparations of rat cerebral cortex ... A chlorpromazine stimulatory effect upon iron uptake from 55Fe-citrate and 55Fe-transferrin by cortical synaptosome preparations of rats was recently demonstrated....
Studies on valinomycin inhibition of synaptosome-fraction protein synthesis.The ionophore valinomycin inhibited adult and neonatal synaptosome fraction protein synthesis with half-maximal inhibition at approximately 10nM....
Cloning of neuronal mtdna variants in cultured cells by synaptosome fusion with mtdna-less cellsSynaptosome cybrids were used to confirm the presence of heteroplasmic mtDNA sequence variants in the human brain....
Isolation of synaptosome and mitochondria from rat brain and immunoprecipitation of synaptosome.Isolation of cortical non-synaptosomal brain mitochondria or synaptosome was achieved by using a discontinuous Percoll gradient....
santé - iate.europa.eu
Molecular mechanisms controlling synaptic vesicle fusion... I establish that the angled-out positioning of the accessory helix does, in fact, occur in solution, and is not due to crystal packing or the truncation of the VAMP2 (the neuronal vesicle-associated SNARE), but rather is due to the fact that its C-terminus is not present....
général - core.ac.uk - PDF: academiccommons.columbia.edu
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate... In addition to genes related to neurite growth and synaptic development, those associated with neuronal vesicle trafficking in the Huntington's disease signalling pathway, were also up-regulated....
 PDF: doaj.org
Botulinum toxin: bioweapon & magic drug... The basis of the phenomenal potency of botulinum toxin is enzymatic; the toxin is a zinc proteinase that cleaves neuronal vesicle associated proteins responsible for acetylcholine release into the neuromuscular junction....
Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour... Alterations in aSyn impair neuronal vesicle formation/transport, and likely contribute to PD pathogenesis by neuronal dysfunction and degeneration....

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santé / milieu naturel - acta.es
santé - iate.europa.eu
santé / sciences naturelles et appliquées - iate.europa.eu
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