Abnormal type iii collagen produced by an exon-17-skipping mutation of the col3a1 gene in ehlers-danlos syndrome type iv is not incorporated into the extracellular matrix.... These normal characteristics of the mutant homotrimers suggested that the loss of ten Gly-Xaa-Yaa triplets (where Gly-Xaa-Yaa is a repetitive amino acid triplet structure in which Xaa and Yaa are other amino acids, proline and hydroxyproline being more common in the Yaa position) did not adversely affect the formation...
Plants do it differently. a new basis for potassium/sodium selectivity in the pore of an ion channel... The selectivity filter of AtCNGC2 represents an alternative mechanism to the well-known GYG amino acid triplet of K(+) channels that has been identified as the critical basis for K(+) over Na(+) permeation through the pore of ion channels
An inhibitor domain in sp3 regulates its glutamine-rich activation domains.... Substitution of the amino acid triplet KEE by alanine residues within this region changed the almost transcriptionally inactive Sp3 into a strong activator....
Ultra-high resolution crystal structure of a dimeric defensin spe10 ... SPE10 associates as a dimer through a unique amino acid triplet involving residues R36–W42–R40....
