Intragenic suppressing mutations correct the folding and intracellular traffic of misfolded mutants of yor1p, a eukaryotic drug transporter*... These mutations are located in the two intracellular loops (ICLs) that interface directly with NBD1, and thus disrupt a functionally important structural module....
3d numerical simulation of flow and temperature on pitot tube...given.The model is created by using structural module of ANSYS, the grids are obtained by ICEM,and the problem is solved and the data post-processing is done by CFX.....
Phospholipase c delta 1 requires a pleckstrin homology domain for interaction with the plasma membrane.... Microinjection of deletion mutants revealed that the region required for membrane attachment and binding of inositol 1,4,5-trisphosphate in vitro corresponded to the pleckstrin homology domain, a structural module described in more than 90 proteins
Synthesis of four-link basic kinematic chains [bkc] with spherical pairs for spatial mechanisms... It is shown that this chain can be used as a structural module for structural-kinematic synthesis of three-dimensional four-link motion generating lever mechanisms by the preset positions of the in-and output links