Regulation of cell invasion and morphogenesis in a three-dimensional type i collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3... MDCK cells were then stimulated with scatter factor/hepatocyte growth factor (SF/HGF) to initiate invasion and tubulogenesis atop either type I collagen or interstitial stroma to determine the ability of MMPs to accelerate, modify, or disrupt morphogenic responses....
Production of salivary microlithiasis in cats by parasympathectomy: light and electron microscopy.... Microliths in the parasympathectomized submandibular glands were detected by light microscopy most often in ductal lumina, followed by acinar lumina, ductal parenchyma, interstitial stroma, and acinar parenchyma....
Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression...5.2-fold increase of SMA in the interstitial stroma, indicatingthat these proteins and the activated fibroblasts play important role in the pathogenesis of cervical cancer....
Extensive laminin and basement membrane accumulation occurs at the onset of bleomycin-induced rodent pulmonary fibrosis.... These findings suggest that bleomycin-induced damage to lung cells causes massive local accumulations of basement membranes, which might be involved in the expansion of the interstitial stroma by stimulating attachment and activation of certain inflammatory cells
