A continuous process for the preparation of 16α,17α[(R)butylidenedioxy]-6α,9α-difluoro-11β,21-dihydroxypregn-4-ene-3,20-dione (rofleponide) is disclosed.
The present invention is concerned with pharmaceutical formulations comprising a combination of (R,R)-formoterol and rofleponide and the use of such formulations in medicine, particularly in the prophylaxis and treatment of respiratory diseases.
The invention provides the use of rofleponide, its esters and salts in the manufacture of a medicament for use in the treatment of irritable bowel syndrome (IBS) and a pharmaceutical formulation for use in such treatment.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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