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Dictionnaire français - anglais

renzapride

santé / chimie - iate.europa.eu

La présente invention a trait à des procédés de préparation de chlorhydrate hydraté de renzapride de Forme II, de chlorhydrate cristallin hydraté de renzapride de Forme II à un niveau égal ou supérieur à 75 % et leurs utilisations.

Formula (I): Renzapride hydrochloride.

santé - wipo.int

The present invention provides processes for preparing Form II renzapride hydrochloride hydrate, crystalline Form II renzapride hydrochloride hydrate at a level of 75% of above and uses thereof.

santé - wipo.int

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Molecular and functional characterization of a 5-ht4 receptor cloned from human atrium ... However, affinities of the h5-HT4A receptor for agonists such as ML10302, BIMU1, renzapride or zacopride were 4–10-fold lower than the ones found in brain....

général - core.ac.uk -

Mediation of 5-hydroxytryptamine-induced tachycardia in the pig by the putative 5-ht4 receptor.Intravenous bolus injections of 5-hydroxytryptamine (5-HT; 3, 10 and 30 micrograms kg-1), 5-methoxytryptamine (5-MeO-T; 3, 10 and 30 micrograms kg-1), renzapride (BRL 24924; 3, 10, 30 and 100 micrograms kg-1) and isoprenaline (0.03,...

PDF: www.pubmedcentral.nih.gov

Ability of 5-ht4 receptor ligands to modulate rat striatal dopamine release in vitro and in vivo.... The release of dopamine from slices of rat striatum continually perfused with Krebs buffer was enhanced by 5-HT4 receptor agonists; 5-HT (10 microM), 5-methoxytryptamine (5-MeOT; 10 microM), renzapride (10 microM) and (S)-zacopride (10 microM) maximally increased dopamine release by 133 +/- 5, 214 +/- 25, 232 +/- 29 and 264 +/- 69%, respectively (mean +/- s.e.mean,...

PDF: www.pubmedcentral.nih.gov

Peristalsis evoked by 5-ht and renzapride: evidence for putative 5-ht4 receptor activation.The effect of 5-hydroxytryptamine and renzapride was studied on the peristaltic reflex elicited in vitro in the guinea-pig ileum....

PDF: www.pubmedcentral.nih.gov

Effect of cisapride and renzapride on gastrointestinal motility and plasma motilin concentration in dogsThe effects of cisapride and renzapride (BRL 24924), on plasma concentration of motilin and gastroduodenal motility were stud-ied in seven dogs with implanted force transducers in the antrum and duodenum....

PDF: jpet.aspetjournals.org

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