The alkb family of fe(ii)/α-ketoglutarate-dependent dioxygenases: repairing nucleic acid alkylation damage and beyondThe AlkB family of Fe(II)- and α-ketoglutarate-dependent dioxygenases is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleobases by oxidative dealkylation....
Directdecarboxylation of 5‑carboxylcytosineby dna c5- methyltransferases... The observedatypical enzymatic C–C bond cleavage reaction provides a plausibleprecedent for a direct reversal of caC to the unmodified state inDNA and offers a unique approach for sequence-specific analysis ofgenomic caC
Human targeted deletions and biological roles of genes involved in repair of alkylation damage... However, there are a few repair mechanisms that are known to be error-free and one of these is direct reversal repair....
Detection of deoxyribonucleic acid damage induced by metal ion interactions and repair of metal ion deoxyribonucleic acid cross-links... Anumber of chemicals were considered for direct reversal repair of copper-DNA cross-links of which ethylenediamine was successful....
