Fgf2 translationally induced by hypoxia is involved in negative and positive feedback loops with hif-1alpha.... The use of siRNAs targeting HIF or FGF2 indicates that FGF2 and HIF-1alpha reciprocally regulate their expression/accumulation, by a negative feedback loop in early hypoxia, followed by a positive feedback loop in late hypoxia....
Fgf2 translationally induced by hypoxia is involved in negative and positive feedback loops with hif-1a... The use of siRNAs targeting HIF or FGF2 indicates that FGF2 and HIF-1a reciprocally regulate their expression/accumulation, by a negative feedback loop in early hypoxia, followed by a positive feedback loop in late hypoxia....
Diabetes-induced oxidative stress in endothelial progenitor cells may be sustained by a positive feedback loop involving high mobility group box-1... Thus, HMGB-1 may play an important role in diabetes-induced oxidative stress in EPCs via a positive feedback loop involving the AGE/reactive oxygen species/HMGB-1 pathway
Positive feedback and mutual antagonism combine to polarize crumbs in the drosophila follicle cell epithelium ... We have built a computer model of apicobasal polarity that suggests that the combination of positive feedback among apical determinants plus mutual antagonism between apical and basal determinants is essential for polarization....
