Molecular variants of the elastin gene contribute to SVAS and Williams syndrome.

It was then she was diagnosed with severe Aortic Valve Stenosis – a very serious heart condition.

The analysis of the elastin gene will provide an early diagnosis of subjects with SVAS and Williams syndrome.

Another and highly infrequent type of hypertension is caused by a constriction of the aorta, the major artery leading from the heart (aortic coarctation).

Aortic valve disease – which includes aortic stenosis – is the main reason for valve repair or replacement and is the focus of several sessions.

Aortic valve disease - which includes aortic stenosis - is the main reason for valve repair or replacement and is the focus of several sessions.

We are able to offer our patients with aortic stenosis less invasive surgical options such as iSAVR.

More specifically, the invention has identified that elastin causes or is involved in the pathogenesis of SVAS and Williams syndrome.

Degenerative or age-related valve disease: mitral valve prolapse, aortic stenosis, post-irradiation valvular disease

Fluid delivery devices having a porous applicator (23a), as well as methods for using the same in the treatment of aortic valve stenosis, are provided.

In very young children, the carotid pulse may be normal, even when severe aortic stenosis is present.

With a growing elderly population, aortic stenosis is anticipated to become a major public health concern.

Symptomatic aortic stenosis is a fatal disease: without intervention, 1 in 5 people will die within 2 years.

Similarly, the effort syncope in a patient with aortic stenosis or blood pressure changes are frequent observation.

In a second embodiment, the elastin gene of an individual to be tested is screened for mutations associated with SVAS or Williams syndrome.