In 1 of 4 subjects treated with intermediate drug doses (30 mg bid), there was a major shift in the viral quasispecies within HR1 at amino acid position 36 (G to D).
The invention also refers to the use of a mouse as defined for testing the efficiency of putative anti-HBV or anti-HCV drugs or for characterizing changes in viral quasispecies during HBV or HCV infection.
Said method makes it possible to determine the viral tropism by quantifying the proportion of viral quasi-species that use one co-receptor or another.
Viral quasi-species: 245 variants have been identified in the vaccine varicella genome with respect to the reference genome used for the analysis (wild genome of the Dumas strain).
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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