The present invention provides a human Rho protein (HRHO) and polynucleotides which identify and encode HRHO.
In Escherichia coli, about half of the transcription events are terminated by the Rho protein.
Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein.
The activated Rho GTPase protein remains associated with the solid support during the detection.
The present invention provides methods of detecting activated Rho GTPase proteins by contacting a solid support with a sample comprising an activated Rho GTPase protein.
Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation.
Single-dose administration of a ROCK inhibitor exhibits a potent analgesic effect after the onset of pathological conditions of cartilage-related diseases such as arthritis deformans.
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