Transgenically produced prolactin and methods of making and using transgenically produced prolactin.

These variants are useful as antagonists of mammal prolactin receptors (PRLR), more particularly of human prolactin receptor (hPRLR).

These variants are useful as antagonists of mammalian prolactin receptors (PRLR), more particularly of human prolactin receptor (hPRLR).

Such polypeptides may for instance be N-terminally pegylated antagonists of the prolactin receptor, such as for instance prolactin variants.

The lactotrope cells that produce prolactin, in the absence of dopamine, secrete prolactin continuously; dopamine inhibits this secretion.

In some embodiments, the methods and compositions include human prolactin, or human prolactin in conjunction with a cytotoxic agent.

Methods are also provided for determining adjustments needed to an abnormal prolactin profile to cause it to conform to the prolactin profile of a healthy subject.

High concentration of Prolactin – High levels of the hormone prolactin in the blood can suppress ovulation.

Prolactin levels: As with other antipsychotics, ziprasidone can elevate levels of the hormone prolactin.

Prolactin levels: As with other antipsychotics, ziprasidone can elevate levels of the hormone prolactin.

a prolactin level test to make sure your body isn’t producing too much prolactin

Prolactin levels: As with other antipsychotics, lurasidone can elevate levels of the hormone prolactin.

Prolactin levels: As with other antipsychotics, lurasidone can elevate levels of the hormone prolactin.

The present invention is concerned with peptides binding to the prolactin receptor, wherein said peptides have an improved binding via binding site 1 (BS1) to the prolactin receptor.

Prolactin – Prolactin is involved in breast development and regulates the production of breast milk.