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pré-ARN messager

pre-messenger RNA

sciences naturelles et appliquées - iate.europa.eu

pré-ARN messager

pre-mRNA

sciences naturelles et appliquées - iate.europa.eu

L'invention concerne des procédés pour influer sur l'expression ou la traduction d'ARN messager, par modification de produits de transcription de pré-ARN messager ou d'ARN messager.

Methods for affecting mRNA expression or translation through the modification of pre-mRNA or mRNA transcripts are described.

santé - wipo.int

Ces molécules pré-thérapeutiques décrites constituent des substrats de réaction de trans-épissure avec un pré-ARN messager qui s'exprime exclusivement dans des cellules cibles spécifiques.

The pre-therapeutic molecules of the invention are substrates for a trans-splicing reaction between the pre-therapeutic molecules and a pre-mRNA which is uniquely expressed in the specific target cells.

santé - wipo.int

La présente invention concerne une nouvelle molécule de trans-épissage de pré-ARNm (RTM) comprenant une région de liaison qui est complémentaire à un pré-ARN messager d'un gène associé à une tumeur, et un domaine codant qui code pour un gène suicide.

The present invention pertains to a novel pre-mRNA trans-splicing molecule (RTM) comprising a binding region which is complementary to a pre mRNA of a tumor associated gene, and a coding domain which encodes for a suicide gene.

sciences naturelles et appliquées - wipo.int

pré-ARN messager

primary transcript

sciences naturelles et appliquées - iate.europa.eu

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Moesm1 of a gene expression microarray for nicotiana benthamiana based on de novo transcriptome sequence assembly...v.5 primary transcript Nbv5tr6241943....

général - core.ac.uk - PDF: figshare.com

Inhibitory effects of activin on gh transcript stability and gh primary transcript expression.... (B) Activin A and B on GH primary transcript expression in carp pituitary cells....

PDF: figshare.com

Mdrl lncrna regulates the processing of mir-484 primary transcript by targeting mir-361.Long noncoding RNAs (lncRNAs) are emerging as new players in gene regulation, but whether lncRNAs operate in the processing of miRNA primary transcript is unclear....

PDF: doaj.org

Mdrl lncrna regulates the processing of mir-484 primary transcript by targeting mir-361>Long noncoding RNAs (lncRNAs) are emerging as new players in gene regulation, but whether lncRNAs operate in the processing of miRNA primary transcript is unclear....

PDF: figshare.com

Wt1 sirna increases the basal and decreases gnrh stimulated expression of endogenous lhβ primary transcript.... Expression of the endogenous LHβ primary transcript, Egr1 primary transcript mRNA, and WT1 protein under conditions where the WT1 (-KTS) variant mRNA was reduced....

PDF: figshare.com

Publications scientifiques

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A functional homing endonuclease in the bacillus anthracis nrde group i intron▿ †... Here, we show that the nrdE pre-mRNA is spliced and that the homing endonuclease cleaves an intronless nrdE gene 5 nucleotides (nt) upstream of the intron insertion site, producing 2-nt 3′ extensions....

sciences naturelles et appliquées - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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An artificial riboswitch for controlling pre-mrna splicing... Here it is shown for the first time that a riboswitch can be engineered to regulate pre-mRNA splicing in vitro....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Small molecule control of pre-mrna splicing... Here, a system is described in which a nontoxic derivative of the small molecule rapamycin is used to control pre-mRNA splicing in vitro....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Regulation of pre-mrna splicing in xenopus oocytes by targeted 2′-o-methylationThe 2′-OH group of the branch point adenosine is a key moiety to initiate pre-mRNA splicing....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Cis requirements for alternative splicing of the cardiac troponin t pre-mrna.The cardiac troponin T (cTNT) pre-mRNA splices 17 exons contiguously but alternatively splices (includes or excludes) the fifth exon....

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov