Disclosed is a process for preparing Tebipenem Pivoxil and analogues thereof.
The present invention relates to co-precipitated amorphous cefditoren pivoxil dosage forms and processes for their preparation.
The amorphous cefditoren pivoxil and one or more water insoluble carriers are co-precipitated from the solution.
A solid dispersion composition which enables noncrystalline cefditoren pivoxil to be held in a suspension for long.
A process for producing cefcapene pivoxil methanesulfonate and, with the use thereof as an intermediate, corresponding hydrochloride.
The present invention also relates to a method of treating infections using highly pure amorphous and crystalline forms of cefditoren pivoxil.
A composition of an amorphous cefditoren pivoxil excellent in stability and releasability; and a process for producing the amorphous composition.
The present invention relates to pharmaceutical tablet formulations comprising cefditoren pivoxil to be used in the treatment of the infectious diseases caused by gram positive and gram negative bacteria.
Yellow and powdery compositions consisting of particles composed of a homogeneous mixture of amorphous cefditoren pivoxil with a water-soluble polymer additive and being orally administrable.
The present invention relates to amorphous cefditoren pivoxil granules having improved solubility, absorption and wetting characteristics with a reduced bitter taste, and processes for the preparation thereof.
By further adding a water-soluble polyphosphate to the composition, it is possible to prevent the elution ratio of cefditorene pivoxil from being decreased during storage under severe conditions.
The present invention relates to pharmaceutical tablet formulations comprising cefditoren pivoxil to be used in the treatment of infectious diseases caused by gram positive and gram negative bacteria.
In this composition, the bitterness of cefditorene pivoxil is relieved and the properties thereof relating to the dissolution rate in water, concentration and elution ratio are improved.
The present invention relates to a highly pure cefditoren pivoxil having purity above about 98.5% and total impurity content less than about 3.0% when measured by HPLC.
The highly pure cefditoren pivoxil has a purity greater than 98.5% and contains less than 1.0% of the E-isomer impurity and less than 1 % of the Δ2isomer impurity.
The present invention relates to water dispersible forms comprising cefditoren pivoxil and/or pharmaceutically acceptable salts, hydrates, solvates, esters, amorphous and crystal forms and/or a combination thereof.
The present invention provides a composition comprising a cefditoren, or a salt, derivative, prodrug, or other form thereof, for example, cefditoren pivoxil, useful in the treatment and prevention of infections and related conditions.
Preferably, the cephalosporin is cefcapene pivoxil or a salt thereof which can be released from the dosage form in an erodable, diffusion and/or osmotic-controlled release profile.
The process includes preparing a solution of crystalline cefditoren pivoxil in one or more solvents; dispersing one or more water insoluble carriers in the solution; and removing the solvent.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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