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pirménol

chimie / général / santé - iate.europa.eu eur-lex.europa.eu
Pirmenol, a new antiarrhythmic agent: initial study of efficacy, safety and pharmacokineticsSUMMARY Pirmenol (CI-845), a new antiarrhythmic drug, was studied for the first time in humans to es-tablish a minimum effective i.v....
santé / vie sociale - core.ac.uk - PDF: circ.ahajournals.org

Publications scientifiques

Pharmacokinetics and pharmacodynamics of pirmenol enantiomers in coronary artery ligated dogsThe pharmacokinetics and pharmacodynamics of pirmenol enantiomers were investigated in coronary artery ligated mongrel dogs....
général - core.ac.uk - PDF: dx.doi.org
Pharmacokinetics and pharmacodynamics of pirmenol enantiomers in coronary artery ligated dogs... Reduction in frequency of premature ventricular complexes (PVCs) was determined following intravenous administration of 5-mg/kg doses of racemic pirmenol (n) 5), (+)-pirmenol (n) 4), and (−)-pirmenol (n) 4), each given as a 5-min infusion....
général - core.ac.uk - PDF: deepblue.lib.umich.edu
Pharmacokinetics of pirmenol enantiomers and pharmacodynamics of pirmenol racemate in patients with premature ventricular contractionsThe pharmacokinetics and pharmacodynamics of pirmenol were investigated in 12 patients with premature ventricular contractions (PVCs) after oral administration of racemic pirmenol, 100mg and 200 mg every 12 hours....
général - core.ac.uk - PDF: deepblue.lib.umich.edu
Stereoselective high-performance liquid chromatographic assay for pirmenol enantiomers in dog plasmaPirmenol enantiomers in dog plasma were quantified using a stereospecific high-performance liquid chromatographic method with ultraviolet detection at 262 nm....
général - core.ac.uk - PDF: dx.doi.org


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