Relation between debrisoquine oxidation phenotype and morphological, biological, and pathological variables in a large population... A single dose of 10 mg of debrisoquine sulfate was admin-istered to determine the oxidation phenotype....
Lack of relationship between debrisoquine oxidation phenotype and the pharmacokinetics of quinine.The relationship between debrisoquine oxidation phenotype and the pharmacokinetics of quinine after a single dose (600 mg) of quinine sulphate was studied in eight extensive metabolizers (EM) and five poor metabolizers...
Stereoselective metabolism of metoprolol in caucasians and nigerians--relationship to debrisoquine oxidation phenotype.The relationship between debrisoquine oxidation phenotype and the stereoselective metabolism of metoprolol was investigated in populations of British Caucasians (n = 139) and Nigerian subjects (n = 117)....
Lack of relationship between debrisoquine oxidation phenotype and the pharmacokinetics and first dose effect of prazosin.The relationship between debrisoquine oxidation phenotype and the pharmacokinetics and pharmacodynamics of a single oral dose of prazosin has been studied in eight hypertensive patients (four extensive and four poor...
