Also uses and methods of use of these biosynthetic random coil polypeptides or polypeptide segments or said conjugates are described.

Protein folding is the process by which a protein assumes its functional shape—from a random coil into a serviceable three-dimensional structure.

The methods entail assessing the fraction of a sample of GA that is in alpha-helical conformation and/or assessing the fraction of a sample of GA that is in random coil conformation.

The random coil only forms when the intermolecular forces between the polymer and the solvent are equal to the forces between the solvent molecules themselves and the forces between polymer chain segments.