Dictionnaire français - anglais

paromomycine

santé / général - iate.europa.eu eur-lex.europa.eu
La présente invention concerne un procédé de purification de paromomycine marquée au tritium ([3H]paromomycine), de la paromomycine tritiée hautement pure obtenue par ledit procédé et une composition comprenant ladite paromomycine.

The present invention concerns a process for the purification of tritium markedparomomycin ([3H]paromomycin), highly pure tritiated paromomycin obtained by said process and a composition comprising said paromomycin.

chimie - wipo.int
La paromomycine agit de façon concentration-dépendante.

Paromomycin acts in a concentration-dependant manner.

général - CCMatrix (Wikipedia + CommonCrawl)
La souche mof4-1 est plus sensible à la paromomycine aminoglycosidique qu'une souche upf1Δ, et l'efficacité de décalage du cadre est augmentée dans une souche mof4-1 cultivée en présence de la paromomycine.

The mof4-1 strain is more sensitive to the aminoglycoside paromomycin than a upf1Δ strain, and frameshifting efficiency increases in a mof4-1 strain grown in the presence of paromomycin.

santé - wipo.int
La présente invention a pour objet un traitement oral de leishmaniose viscérale comprenant de la paromomycine et un amplificateur de la perméation qui augmente la biodisponibilité de la paromomycine d'au moins 20 %.

A composition for oral treatment of visceral leishmaniasis comprises paromomycin and a permeation enhancer that increases oral bioavailability of the paromomycin to at least 20%.

santé - wipo.int
La présente invention concerne en outre l'utilisation de ladite paromomycine pour des tests d'écotoxicité.

The present invention further concerns the use of said paromomycin for ecotoxicity tests.

chimie - wipo.int
Antibiotic control of mycoplasma in tissue culture... laidlawii type B cells to neomycin resulted in a 50-fold increase in resistance, and the resistant strain was also resistant to gentamicin, kanamycin, neomycin, and paromomycin....
santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Mutations in 16s ribosomal rna disrupt antibiotic--rna interactions.... Chemical probing of mutant and wild-type ribosomes in the presence of paromomycin indicates that interactions between the antibiotic and 16S rRNA in mutant ribosomes are disrupted....
Combination of paromomycin and miltefosine promotes tlr4dependent induction of antileishmanial immune response inObjectives: To evaluate the in vitro activity of antileishmanial drugs, paromomycin and miltefosine, to generate Th-1-biased immunomodulation in hosts against intracellular Leishmania donovani....
High resistance of pseudomonas aeruginosa to paromomycin, an agent used for selective bowel decontamination (sbd)[english] Background: Paromomycin is used for selective bowel decontamination (SBD) in patients undergoing bone marrow transplantation in many hospitals, but there are no published resistance data ...
 PDF: doaj.org
Paromomycine
général - eur-lex.europa.eu
L’activité bactéricide de la paromomycine est attribuée principalement à ses liaisons irréversibles avec les ribosomes.

The bactericidal activity of paromomycin is mainly attributed to its irreversible binding to ribosomes.

général - CCMatrix (Wikipedia + CommonCrawl)
Les antibiotiques aminoglycosides, comme la paromomycine, peuvent entraîner une ototoxicité ou une néphrotoxicité.

Aminoglycoside antibiotics such as paromomycin can cause phenomena such as oto- and nephrotoxicity.

général - CCMatrix (Wikipedia + CommonCrawl)
Pour aider à garder la constante de quantité, vous devez prendre paromomycine sur un horaire régulier.

To help keep the amount constant, you must take paromomycin on a regular schedule.

général - CCMatrix (Wikipedia + CommonCrawl)
intestinal asymptomatique E histolytica Les infections peuvent être traitées avec la paromomycine ou iodoquinol.

Asymptomatic intestinal E histolytica infections can be treated with paromomycin or iodoquinol.

général - CCMatrix (Wikipedia + CommonCrawl)
La paromomycine modifie la lecture de l’ARN messager, ce qui perturbe la synthèse protéique.

Paromomycin changes the reading of messenger-RNA, which disrupts protein synthesis.

général - CCMatrix (Wikipedia + CommonCrawl)
Antibiotic control of mycoplasma in tissue culture... laidlawii type B cells to neomycin resulted in a 50-fold increase in resistance, and the resistant strain was also resistant to gentamicin, kanamycin, neomycin, and paromomycin....
santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Mutations in 16s ribosomal rna disrupt antibiotic--rna interactions.... Chemical probing of mutant and wild-type ribosomes in the presence of paromomycin indicates that interactions between the antibiotic and 16S rRNA in mutant ribosomes are disrupted....
Combination of paromomycin and miltefosine promotes tlr4dependent induction of antileishmanial immune response inObjectives: To evaluate the in vitro activity of antileishmanial drugs, paromomycin and miltefosine, to generate Th-1-biased immunomodulation in hosts against intracellular Leishmania donovani....
High resistance of pseudomonas aeruginosa to paromomycin, an agent used for selective bowel decontamination (sbd)[english] Background: Paromomycin is used for selective bowel decontamination (SBD) in patients undergoing bone marrow transplantation in many hospitals, but there are no published resistance data ...
 PDF: doaj.org

Publications scientifiques

Biochemical characterization of two cloned resistance determinants encoding a paromomycin acetyltransferase and a paromomycin phosphotransferase from streptomyces rimosus forma paromomycinus.The mechanism conferring resistance to paromomycin in Streptomyces rimosus forma paromomycinus, the producing organism, was studied at the level of both protein synthesis and drug-inactivating enzymes....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Inhibition of antiassociation activity of translation initiation factor 3 by paromomycinThe effect of paromomycin on the interaction of ribosomal subunits was studied....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Randomized, double-blinded, phase 2 trial of wr 279,396 (paromomycin and gentamicin) for cutaneous leishmaniasis in panama... In this randomized, double-blinded Phase 2 trial, 30 patients with Leishmania panamensis cutaneous leishmaniasis were randomly allocated (1:1) to receive once daily topical treatment with WR 279,396 (15 % paromomycin + 0.5...
santé - core.ac.uk - PDF: ftp:
Antimony-resistant clinical isolates of leishmania donovani are susceptible to paromomycin and sitamaquine▿... We aimed to generate the baseline data on natural in vitro susceptibility to paromomycin and sitamaquine in Leishmania donovani field isolates from VL patients (n = 20) coming from zones of varying sodium antimony gluconate (SAG) resistance....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Differential effects of paromomycin on ribosomes of leishmania mexicana and mammalian cells ▿Paromomycin, an aminoglycoside antibiotic having low mammalian cell toxicity, is one of the drugs currently used in the chemotherapy of cutaneous and visceral leishmaniasis....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Synonymes et termes associés français

Traductions en contexte français - anglais

L'invention concerne un système vectoriel de transformation de levure mettant en oeuvre un gène de résistance à la paromomycine.

A yeast transformation vector system using a paramomycin-resistance gene.

chimie - wipo.int
Pour aider à garder la constante de quantité, vous devez prendre paromomycine sur un horaire régulier.

To help keep the amount constant, you must receive tobramycin on a regular schedule.

général - CCMatrix (Wikipedia + CommonCrawl)
Ceux-ci comprennent la paromomycine, la bacitracine, le cisplatine, la vancomycine, l’amphotéricine B, polymyxine B, la colistine et viomycine.

These include paromomycin, bacitracin, cisplatin, vancomycin, amphotericin B, polymyxin B, colistin, and viomycin.

général - CCMatrix (Wikipedia + CommonCrawl)
La présente invention concerne un moyen d'inhibition efficace d'infections dues à la leishmania par application topique de compositions renfermant de la paromomycine et de la gentamicine.

This invention relates to a means of effectively inhibiting leishmania infections by topical application of compositions containing paromomycin and gentamicin.

santé - wipo.int
En Afrique, la meilleure option disponible, un traitement combinant antimoniés pentavalents et paromomycine, nécessite des injections nombreuses et douloureuses.

In Africa, the best available treatment is still a combination of pentavalent antimonials and paromomycin, which is toxic and requires a number of painful injections.

général - CCMatrix (Wikipedia + CommonCrawl)
La paromomycine possède une action à large spectre contre de nombreuses bactéries Gram positif ou négatif, y compris E. coli.

Paromomycin has broad spectrum activity against numerous Gram-positive and Gram-negative bacteria, including E. coli.

général - CCMatrix (Wikipedia + CommonCrawl)
La paromomycine sélectionne à haute fréquence des résistances et des résistances croisées à de nombreux autres aminoglycosides dans la flore intestinale.

Paromomycin selects for resistance and cross-resistances at high frequency against a variety of other aminoglycosides among intestinal bacteria.

général - CCMatrix (Wikipedia + CommonCrawl)
La présente invention concerne des dérivés amphiphiles d'aminoglycoside (AG), en particulier des dérivés de tobramycine, de kanamycine A et de paromomycine comprenant des chaînes latérales hydrophobes liées au fragment d'AG par divers lieurs.

The present invention relates to amphiphilic aminoglycoside (AG) derivatives, especially derivatives of tobramycin, kanamycin A and paromomycin comprising hydrophobic side chains linked to the AG moiety by various linkers.

chimie - wipo.int
L'institut pour la santé mondiale a développé la paromomycine, dont les résultats ont conduit à son inscription comme médicament orphelin.

The Institute for OneWorld Health has developed paromomycin, results with which led to its approval as an orphan drug.

général - CCMatrix (Wikipedia + CommonCrawl)
Après cette période de repos, on propage les plantes transgéniques à partir du tissu de la plante transformée en présence d'un agent de sélection tel la paromomycine sulfate ou la généticine.

After this rest period, transgenic plants are selectively propagated from the transformed plant tissue in the presence of a selection agent such as paromomycin sulphate or geneticin.

sciences naturelles et appliquées - wipo.int
Maladie légère à modérée qui comprend la diarrhée ou la dysenterie peuvent être traités avec le métronidazole suivi soit par paromomycine ou iodoquinol.

Mild to moderate disease that includes diarrhea or dysentery can be treated with metronidazole followed by either paromomycin or iodoquinol.

général - CCMatrix (Wikipedia + CommonCrawl)
Suite à l'administration par voie orale de la paromomycine, aucune absorption n'est observée et la molécule est éliminée telle quelle dans les fèces.

Following oral administration of paromomycin, hardly any absorption takes place and the molecule is eliminated unchanged via the faeces.

général - CCMatrix (Wikipedia + CommonCrawl)
La paromomycine possède une action à large spectre contre de nombreuses bactéries Gram positif ou Gram négatif, y compris E. coli.

Paromomycin has broad spectrum activity against numerous Gram-positive and Gram-negative bacteria, including E. coli.

général - CCMatrix (Wikipedia + CommonCrawl)
Afin d'obtenir la posologie voulue, la consommation d'eau / de lait / d'aliment d'allaitement doit être surveillée, et la concentration de paromomycine doit être ajustée en conséquence.

In order to obtain the correct dosage, drinking water/milk/milk replacer uptake has to be monitored and the concentration of paromomycin has to be adjusted accordingly.

général - CCMatrix (Wikipedia + CommonCrawl)
Suite à l’administration par voie orale de la paromomycine, pratiquement aucune absorption n’est observée et la molécule est éliminée telle quelle dans les fèces.

Following oral administration of paromomycin, hardly any absorption takes place and the molecule is eliminated unchanged via the faeces.

général - CCMatrix (Wikipedia + CommonCrawl)


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