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omacétaxine mépésuccinate

omacetaxine mepesuccinate

général - eur-lex.europa.eu
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Omacetaxine may have a role in chronic myeloid leukaemia eradication through downregulation of mcl-1 and induction of apoptosis in stem/progenitor cells... Omacetaxine mepesuccinate, a first in class cetaxine, has been evaluated by clinical trials in TKI-insensitive/resistant CML....
général - core.ac.uk - PDF: eprints.gla.ac.uk
Validation of high-performance liquid chromatography-tandem mass spectrometry assays quantifying omacetaxine mepesuccinate and its 4'-des-methyl and cephalotaxine metabolites in human plasma and urineOmacetaxine mepesuccinate (hereafter called omacetaxine) is a modified cephalotaxine and is registered (Synribo®) for the treatment of adult patients with chronic myeloid leukemia...
 PDF: www.loc.gov
Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines... However, patient resistance and cytotoxicity make secondary lines of treatment, such as omacetaxine mepesuccinate, a necessity....
 PDF: hdl.handle.net
Metabolite profiling of 14c-omacetaxine mepesuccinate in plasma and excreta of cancer patientsOmacetaxine mepesuccinate (hereafter referred to as omacetaxine) is a protein translation inhibitor approved by the US Food and Drug Administration for adult patients with chronic...
 PDF: figshare.com


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