Causation of apoptosis by cyclopamine is by a non-genotoxic mechanism.

The invention discloses gene signatures for predicting onset of non-genotoxic hepatocarcinogenicity in a subject.

To date, there is no evidence that resolves whether OTA causes cancer strictly through a genotoxic or non-genotoxic mechanism.

A standard battery of genotoxicity tests indicated that buprenorphine is non-genotoxic.

A standard battery of genotoxicity tests indicated that buprenorphine is nongenotoxic.

The method involves contacting mammalian cells with a composition that contains a non-genotoxic inducer of p53 (NGIP).

Enbrel was considered to be non-genotoxic from a battery of in vitro and in vivo studies.

If the observed UDMH carcinogenicity is due to a non-genotoxic mechanism, the above indicated doses should be considered to be toxicological thresholds.

Etanercept was considered to be non-genotoxic from a battery of in vitro and in vivo studies.

Etanercept was considered to be non-genotoxic from a battery of in vitro and in vivo studies.

Based on results of a full range of standard genotoxicity tests, aripiprazole was considered non-genotoxic.

Based on results of a full range of standard genotoxicity tests, aripiprazole was considered non-genotoxic.

Based on results of a full range of standard genotoxicity tests, aripiprazole was considered non- genotoxic.

Based on results of a full range of standard genotoxicity tests, aripiprazole was considered non- genotoxic.

Based on results of a full range of standard genotoxicity tests, aripiprazole was considered non-genotoxic.