The invention relates to a method for modifying a template double stranded polynucleotide, especially for characterisation using nanopore sequencing.
However, "nanopore sequencing" is prone to high inaccuracy because DNA usually passes through very fast.
By sequentially locking each monomer unit in the potential well (114), nanopore sequencing of DNA with single base resolution can be achieved.
The observation that a passing strand of RNA containing different bases results in different blocking levels has led to the nanopore sequencing hypothesis.
In nanopore sequencing, DNA passes through a tiny pore in a membrane, much like a thread goes through a needle.
Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores.
In some embodiments, the device comprises a nanopore device, and wherein the nanopore device comprises a single cell of a nanopore array.
Low dielectric materials are described herein that comprise a plurality of pores or nanopores in addition to the ultrananopores.
The present invention relates to nanopore membranes, methods for manufacturing such nanopore membranes, and uses thereof.
Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof.
The nanoporous surface layer contains a plurality of nanopores.
A first physical measurement of the nanopores is evaluated.
The nanopores providing a flow through porosity.
The invention further relates to a nanoporous part.
Devices are also provided herein for measuring DNA with nano-pores sized to allow DNA to pass through the nano-pore.
Nanopores are extremely sensitive single-molecule sensors.
Nanopores are extremely sensitive single-molecule sensors.
According to the invention the electrodes include a layer of carbon particles having a narrow distribution of nanopores therein, the pore sizes of the nanopores being adapted to fit the ion sizes of the electrolyte.
The nanosized pores have a pore size from 0.15 nm to 50 nm, and the sub-nanosized pores have a pore size from 0.05 nm to 0.5 nm.
This sensor has nanosized pores having a highly orderly periodic pore structure, and the wall surface of each nanosized pore is provided with sub-nanosized pores.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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