Function of bruton's tyrosine kinase during b cell development is partially independent of its catalytic activity... In contrast, transgenic expression of kinase-inactive K430R-Btk completely reconstituted lambda usage in Btk-deficient mice, but the defective modulation of pre-B cell surface markers, peripheral B cell survival, and BCR-mediated NF-kappaB induction were partially corrected....
Impaired autonomic responses to emotional stimuli in autoimmune limbic encephalitis... The results point to a defective modulation of sympathetic responses during emotional stimulation in patients with LE, probably due to impaired functioning of the amygdala
Impaired autonomic responses to emotional stimuli in autoimmune limbic encephalitis... The results point to a defective modulation of sympathetic responses during emotional stimulation in patients with LE, probably due to impaired functioning of the amygdala
Altered ryr2 regulation by the calmodulin f90l mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death ... Moreover, CaMF90L displays reduced RyR2 interaction and defective modulation of [3H]ryanodine binding....
