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mitindomide

santé / chimie - iate.europa.eu
Mitindomide is a catalytic inhibitor of dna topoisomerase ii that acts at the bisdioxopiperazine binding siteThe antitumor drug mitindomide (NSC 284356) was shown to inhibit the decatenation activity of human and Chinese hamster ovary (CHO) topoisomerase II [DNA topoisomerase (ATP-hy-drolyzing), EC 5.99.1.1]....
général - core.ac.uk - PDF: molpharm.aspetjournals.org


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