The x-ray crystal structure of 4-diphenylcarbamyl-n-methyl-piperidine methobromide (the carbamate analogue of 4-damp methiodide).... Crystals of 4-diphenylcarbamyl-N-methylpiperidine methobromide contain 2 conformers, one with the ester group equatorial and the other with the ester group axial to the piperidine ring....
Affinities of the protonated and non-protonated forms of hyoscine and hyoscine n-oxide for muscarinic receptors of the guinea-pig ileum and a comparison of their size in solution with that of atropine....9.9, at least as active as hyoscine methobromide (log K = 9.85)....
The affinity of some acetylenic analogues of 4-damp methobromide for muscarinic receptors in guinea-pig ileum and atria.... The diphenylcarbamyl ester of 4-hydroxy-N-methylpiperidine methobromide has less than one-thousandth of the activity of the diphenylacetyl ester (4-DAMP methobromide) and is not selective....
Effect of transdermally administered hyoscine methobromide on nocturnal acid secretion in patients with duodenal ulcer.... A study was conducted into the effectiveness of transdermal delivery of hyoscine methobromide using a new system which releases the drug into the circulation at a controlled rate....
