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mésulergine

santé / chimie - iate.europa.eu
Site-directed mutagenesis of a single residue changes the binding properties of the serotonin 5-ht2 receptor from a human to a rat pharmacology AbstractMesulergine displays approximately 50-fold higher affinity for the rat 5-HT2 receptor than for the human receptor....
santé - core.ac.uk -

Publications scientifiques

[(3)h]-mesulergine labels 5-ht(7) sites in rat brain and guinea-pig ileum but not rat jejunum... Studies were performed using [(3)H]-mesulergine, as it has a high affinity for 5-HT(7) receptors....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Autoradiographic distribution of 5-ht(7) receptors in the human brain using [(3)h]mesulergine: comparison to other mammalian species... Binding studies were performed in rat frontal cortex membranes using 10 nM [(3)H]mesulergine in the presence of raclopride (10 μM) and DOI (0.8...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Block of the delayed rectifier k+ channel by (±) skf83959 in rat hippocampal neurons....by (±) SKF83959 (100 µM) in the presence of D1 receptor antagonist SCH23390 (20 µM, n = 6), or α1-adrenoceptor antagonist prazosin (10 µM, n = 6), or 5-HT receptor antagonist mesulergine (10 µM, n = 6)....
général - core.ac.uk - PDF: figshare.com
An endothelial 5-ht receptor that mediates relaxation in guinea-pig isolated jugular vein resembles the 5-ht1d subtype.... An endothelial 5-HT receptor was studied in the presence of mesulergine (at 10.0...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov


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