Comparison of trna motions in the free and ribosomal bound structures... For the intact ribosome, its major parts, the 30S and the 50S subunits, are found to have counterrotational motions in the first few slowest modes, which are consistent with the experimentally observed ratchet motion....
Sine-gordon ratchets with general periodic, additive, and parametric driving forces... Using a collective coordinate theory with two degrees of freedom, we show that the ratchet motion of kinks appears as a consequence of a resonance between the oscillations of the momentum and the width of the kink....
Interaction strengths between the ribosome and trna at various steps of translocation... Based on the interaction strengths between the ribosome and tRNA under these conditions, 1), we concluded that tRNA interaction with the 30S subunit is far more important than the interaction with the 50S subunit in the mechanism of translocation; and 2), we propose a mechanism of translocation where the ribosomal ratchet motion, with the aid of EF-G, drives tRNA translocation
Discrete soliton ratchets driven by biharmonic fields... In comparison with the previouslystudied continuum case, the discrete case shows a number of new features:non-zero depinning threshold for the driving amplitude, locking to the rationalfractions of the driving frequency, and diffusive ratchet motion in the case ofweak intersite coupling.Comment:...
