A lipid particle can include a plurality of cationic lipids, such as a first cationic lipid and a second cationic lipid.

A neutral cationic lipid and liposomes prepared from the neutral cationic lipid are described.

αvβ3 Integrin receptor targeting liposomes comprise a cationic amphiphile such as a cationic lipid, a neutral lipid, and a targeting lipid.

The cationic molecule is preferably a cationic polymer, such as DEAE-Dextran, or a cationic lipid.

The present invention also provides nucleic acid-lipid particles comprising a modified siRNA, a cationic lipid, and a non-cationic lipid, which can further comprise a conjugated lipid that inhibits aggregation of particles.

The lipid particles comprise a cationic lipid, a non-cationic lipid, and an mRNA molecule that is encapsulated within the lipid particle.

In addition to the biodegradable cationic lipid the nanoparticles comprise a non-cationic lipid, polyethylne glycol dipalmitoylglycerol (PEG-DPG) and optionally a sterol.

The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid.

The carrier composition can be prepared by mixing (A) a cationic lipid having a steroid nucleus with (B) a cationic lipid of a quaternary ammonium salt type.

In particular, the invention relates to oligonucleotides encapsulated in a mixture of a cationic lipid, a fusogenic lipid and a PEG lipid.

The present invention provides a compound capable of acting as a cationic lipid, the compound comprises a cholesterol group and a carbohydrate moiety.

The cationic lipid can be DMRIE, possibly coupled with DOPE.

The first cationic lipid can be selected on the basis of a first property and the second cationic can be selected on the basis of a second property.

The invention features a cationic lipid of formula (I), an improved lipid formulation comprising a cationic lipid of formula I and corresponding methods of use.

The emulsion particles comprise an oil core and a cationic lipid.