Flow cytometric analysis of human nucleus pulposus (np) cells.NP cell–alginate 3D composites were exposed to saline, radiocontrast agent (iotrolan), or local anesthetic agents (lidocaine and bupivacaine) for 30, 60, or 120 min, cultured 24 h, then the NP cells were isolated for analysis....
Cytotoxic effects of the radiocontrast agent iotrolan and anesthetic agents bupivacaine and lidocaine in three- dimensional cultures of human intervertebral disc nucleus pulposus cells: identification of the apoptotic pathways... Methods: Healthy human NP cells were cultured for 7 days in three-dimensional (3D) cell–alginate bead composites, and were then exposed to clinically relevant doses of a radiocontrast agent (iotrolan) or local anesthetic (lidocaine or bupivacaine)....
Effects of contrast media and mannitol on renal medullary blood flow and red cell aggregation in the rat kidney ... The CM, namely diatrizoate, iopromide, iohexol, ioxaglate, iotrolan, were given in iodine equivalent doses (1600mg/kg body wt)....
Cytotoxic effects of the radiocontrast agent iotrolan and anesthetic agents bupivacaine and lidocaine in three-dimensional cultures of human intervertebral disc nucleus pulposus cells: identification of the apoptotic pathways...cells.Healthy human NP cells were cultured for 7 days in three-dimensional (3D) cell–alginate bead composites, and were then exposed to clinically relevant doses of a radiocontrast agent (iotrolan) or local anesthetic (lidocaine or bupivacaine)....
