Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of oxycodone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of oxycodone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

There is a significant correlation between the trypsin inhibitor content and the protein content of the sweet potato variety.

Knottins variants based on EETI (Ecballium elaterium trypsin inhibitor) and AgRP (Agouti-related protein) were engineered to contain integrin- binding loops.

The present invention encompasses a preparation and method whereby a trypsin inhibitor and free essential amino acids are used simultaneously in the form of an oral preparation to reduce weight.