Neurogenic placodes provide migratory enteric sensory neural progenitors in response to endothelin signaling pathway... Abnormal development of ENS may cause the congenital aganglionic megacolon phenotype as Hirschsprung’s disease (HSCR)....
Null mutation of endothelin receptor type b gene in spotting lethal rats causes aganglionic megacolon and white coat color.Mutations in the gene encoding the endothelin receptor type B (EDNRB) produce congenital aganglionic megacolon and pigment abnormalities in mice and humans....
Functional aerophagia in children: a frequent, atypical disorder... Mechanical intestinal obstruction, chronic intestinal pseudo-obstruction, malabsorption and congenital aganglionic megacolon were ruled out....
Congenital aganglionic megacolonTwenty-one pull-through procedures for congenital aganglionic megacolon (Hirschsprung's disease) have been performed at the Los Angeles Children's Hospital since the adoption of the etiological concept of a distal ...
