Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis... We found that in Sprague-Dawley rats with traumatic SCI, the expressions of autophagy light">marker Light Chain 3 (LC3) and Beclin1 were decreased with concomitant accumulation of autophagy substrate protein p62 and ubiquitinated proteins, indicating an impaired autophagic...
P62/sqstm1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death... The autophagic light">marker light chain 3 (LC3) colocalized with p62 bodies and coimmunoprecipitated with p62, suggesting that these two proteins participate in the same complexes....
Research article transforming growth factor tgfβ increases levels of microtubule-associated protein map1s and autophagy flux in pancreatic... Microtubule-associated protein MAP1S (originally named C19ORF5) is a widely-distributed homologue of neuronal-specific MAP1A and MAP1B with which autophagy light">marker light chain 3 (LC3) was originally co-puri-fied....
