Dr Reichenbachs team now use lentiviral, self-inactivating gene therapy that she describes as more efficient and safer.
The Salmonella have in addition to an RpoS+ phenotype an inactivating mutation in one or more genes which render the microbe attenuated, and a recombinant gene capable of expressing a desired protein.
More specifically, the invention concerns the inactivating deletion of the interleukin-1 receptor antagonist gene to produce a knock-out non-human mammal with decreased or completely suppressed expression of the endogenous gene.
In this example, since gene “x” is mutated to a pseudogene in the common ancestor of species A, B and C, we would expect to find this pseudogene, with the same exact inactivating mutation, in these three species.
Dr Reichenbachs team now use lentiviral, self-inactivating gene therapy that she describes as more efficient and safer.
The Salmonella have in addition to an RpoS+ phenotype an inactivating mutation in one or more genes which render the microbe attenuated, and a recombinant gene capable of expressing a desired protein.
More specifically, the invention concerns the inactivating deletion of the interleukin-1 receptor antagonist gene to produce a knock-out non-human mammal with decreased or completely suppressed expression of the endogenous gene.
In this example, since gene “x” is mutated to a pseudogene in the common ancestor of species A, B and C, we would expect to find this pseudogene, with the same exact inactivating mutation, in these three species.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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