Difference in the potency of alpha 2-adrenoceptor agonists and antagonists between the pithed rabbit and rat.... The dose-response curve for noradrenaline was shifted to the right by prazosin (1 mg kg-1) and was shifted to a smaller extent by rauwolscine (1 mg kg-1) or imiloxan (10 mg kg-1)....
The role of several α(1)- and α(2)-adrenoceptor subtypes mediating vasoconstriction in the canine external carotid circulation... The responses to phenylephrine were selectively antagonized by the antagonists, 5-methylurapidil (α(1A)) or BMY7378 (α(1D)), but not by L-765,314 (α(1B)), BRL44408 (α(2A)), imiloxan (α(2B)) or MK912 (α(2C))....
Sodium modulation of 3h-agonist and 3h-antagonist binding to alpha 2-adrenoceptor subtypes.... In the neonatal rat lung, NaCl had no significant effect on the affinity of prazosin for [3H]-RS-15385-197 binding; however, imiloxan affinity was increased 13 fold....
Alpha 2-autoreceptor subclassification in rat isolated kidney by use of short trains of electrical stimulation....0.1 microM) and imiloxan (0.1,...
