Comparisons of the antiviral activity in vitro of some non-steroidal anti-inflammatory drugsIn cultures of mouse or chick embryo ceils several non-steroidal anti-inflammatory drugs (salicylates, Ibufenac, phenylbutazone, Indomethacin, flufenamic and mefenamic acids, CI-583, and chloroquine) inhibit the multi-plication of various viruses (encephalomyocarditis, S ndbis,...
Significantly different covalentbinding of oxidativemetabolites, acyl glucuronides, and s‑acyl coa conjugates formed from xenobiotic carboxylic acidsin human liver microsomes... While ibuprofenand tolmetin are still on the market, ibufenac, fenclozic acid, tienilicacid, suprofen, and zomepirac were stopped before their launch orwithdrawn....
Inhibition of faah by the enantiomers of flu-am1 and ibu-am5 and by ibufenac-am1.Structures of the compounds are shown in Panels A-C: A, Flu-AM1; B, Ibu-AM5; C, ibufenac-AM1....
Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albuminThe disposition of ibuprofen and ibufenac, an analog of ibuprofen with a history of severe adverse reactions, was investigated in Rhesus monkeys after oral administration....
