Nonspherocytic hemolytic anemia due to hexokinase deficiency
3-O-Methyl-D-Glucose is a non-metabolizable glucose analogue that is not phosphorylated by hexokinase.
Non-spherocytic hemolytic anemia due to hexokinase deficiency
The enzyme hexokinase is shown as a simple ball-and-stick molecular model.
The enzyme hexokinase is shown as a conventional ball-and-stick molecular model.
The invention provides isolated nucleic acids molecules, designated 50365 nucleic acid molecules, which encode novel hexokinase members.
Hexokinase III/C is substrate-inhibited by glucose at physiologic concentrations.
First, it activates the enzyme hexokinase, which phosphorylates glucose, trapping it within the cell.
Hexokinase III/C is substrate-inhibited by glucose at physiologic concentrations.
Mice with the APOE4 allele, on the other hand, had reduced hexokinase activity over time.
The drug triggers the dissociation of HK2 (hexokinase 2) from mitochondrial VDAC (voltage dependent anion channel) leading, among other effects, to apoptosis and death of the malignant cells.
The invention also discloses the uses of the polynucleotide, which encodes a human hexose kinase 13.
The invention discloses the antagonist against the polypeptide and therapeutics thereof.
The invention discloses the antagonist against the polypeptide and therapeutics thereof.
The invention discloses a new kind of polypeptide-hexokinase protein 12 and polynucleotide encoding said polypeptide and a process for producing said polypeptide by DNA recombinant methods.
Nonspherocytic haemolytic anaemia due to hexokinase deficiency is characterised by severe hemolysis, appearing in infancy.
The enzyme hexokinase is contained in or on a support (101; 201; 301) of the sensor.
A method of changing the activity of hexokinases in a plant sink comprising introducing into the plant a gene encoding a fungal hexokinase.
The invention relates to sensor (100; 200; 300; 400) for detecting glucose.
The present invention concerns a human hexose kinase 13 and polynucleotide encoding it.
For example, the first intermediate in glycolysis, glucose-6-phosphate, inhibits the very enzyme that produces it, hexokinase.
The invention also concerns the process of producing the polypeptide by recombinant DNA technique.
The invention concerns a human hexokinase protein and polynucleotide encoding it.
The invention also concerns the process of producing the polypeptide by recombinant DNA technique.
Disclosed are methods and genes for manipulating the sugar-sensing capabilities of a plant, involving reducing or increasing the level of a hexokinase protein in a transgenic plant.
Glucose enters the bloodstream through the tubules of the kidneys through the phosphating effect of the hexokinase enzyme on it.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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