The invention relates to the use of heart-specific transcription factors of the basic helix-loop-helix type for treating cardiac power failure.
Δ3-AIB1 mRNA encodes a 130 kDa protein that lacks the N-terminal basic helix-loop-helix and a portion of the PAS dimerization domain.
These fragments, e.g. the basic helix loop helix domain or amino acids 1-141, have substantially the same PPARγ2 promoter repressing activity as the full length polypeptide.
Compositions of the invention include an early flowering 3 (ELF3) maize gene, the promoter for this gene, an Arabidopsis basic helix-loop-helix transcription factor (bHLH-041), and fragments and variants thereof.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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