Because guanabenz has been off the market for many years, it is no longer manufactured anywhere in the world.

The use of guanabenz in the horse provides for a safe, effective, long lasting and rapidly reversible sedative and analgesic which can be used on the standing animal.

The invention is also directed to pharmaceutical compositions comprising guanabenz wherein said compositions are in the form of an aqueous gel or non-aqueous ointment.

Treatment with guanabenz strengthens this stress-response mechanism and helps protect oligodendrocytes from cell death.

Guanabenz appears to enhance the cell's own protective machinery to diminish the loss of myelin," Popko said.

However, before clinical studies could be initiated, the MRF had to identify a contract drug manufacturer to make clinical-grade guanabenz.

Guanabenz will probably not be a standalone drug, but we hope that it can be developed for use in combination with other medications,” Popko said.

Guanabenz will probably not be a standalone drug, but we hope that it can be developed for use in combination with other medications," Popko said.

Atenolol is known to interact with drugs like guanabenz, digoxin, diabetis medication, heart medication, medication for asthma, diet pills, medication for colds and stimulants like caffeine.

We are very pleased guanabenz is now moving into studies in MS patients," said Tassie Collins, Ph.D., Vice President of Translational Medicine at the Myelin Repair Foundation.