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Prnp promoter polymorphisms are associated with bse susceptibility in swiss and german cattleBACKGROUND: Non-synonymous polymorphisms within the prion protein gene (PRNP) influence the susceptibility and incubation time for transmissible spongiform encephalopathies (TSE) in some species such as sheep and humans....

activité agricole - core.ac.uk - PDF: www.pubmedcentral.nih.gov

PrP gene

activité agricole - iate.europa.eu

Publications scientifiques

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Protective effect of the at137rq and arqk176 prp alleles against classical scrapie in sarda breed sheep... All ARQ/ARQ affected sheep (n = 154) and 378 negative ARQ/ARQ controls from four scrapie outbreaks were submitted to sequencing of the PrP gene....

moyen de production agricole / activité agricole / santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine prp gene... A mouse line, Tg(OvPrP4), devoid of the murine PrP gene, was obtained by crossing with PrP knockout mice....

activité agricole / moyen de production agricole / santé - core.ac.uk - PDF: www.pubmedcentral.nih.gov

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Improvement of goat tse discriminative diagnosis and susceptibility based assessment of bse infectivity in goat milk and meat... Our approach integrates the predicted influence of PrP gene polymorphisms on scrapie and BSE susceptibility so that it could potentially be used for the control of field TSE outbreaks in goats....

activité agricole - core.ac.uk - PDF: www.loc.gov

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Clinical trial simulations based on genetic stratification and the natural history of a functional outcome measure in creutzfeldt-jakob disease... The PrP gene sequence was significantly associated with decline relative to any other demographic or investigation factors....

santé / activité agricole - core.ac.uk - PDF: discovery.ucl.ac.uk

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Mechanisms of neuroinvasion by prions: molecular principles and present state of research... Introduction of mutant PrP genes into PrP-deficient mice was used to investigate the structure-activity relationship of the PrP gene with regard to scrapie susceptibility....

santé / activité agricole - core.ac.uk - PDF: www.zora.uzh.ch