For in vivo measurement of suicide gene expression with petThe gene for herpes simplex virus thymidine kinase (HSV-tk) is widely used as a suicide gene in experimental gene therapy of cancer....
A novel bifidobacterium infantis-mediated tk/gcv suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer... In order To search for novel targeted and efficacious treatment, we sought to investigate anti-tumor activity of BI-TK suicide gene therapy system in a rat model of bladder tumors....
An experimental study on cervix cancer with combination of hsv-tk/gcv suicide gene therapy system and 60co radiotherapyAbstract Background To evaluate the killing effect of HSV-TK/GCV suicide gene therapy system combined with 60Co radiotherapy on human cervical cancer Hela cell line in vitro and in vivo, and to explore the radiosensitization by HSV-TK/GCV system....
The war against cancer: suicide gene therapy... One of the most innovative approaches against cancer is suicide gene therapy, in which suicide-inducing transgenes are introduced into cancer cells....
