Isolation, characterization and seasonal variations in the concentration of n-epsilon-(gamma-glutamyl)-lysine isodipeptide in the blood plasma of the winter flounder (pseudopleuronectes americanus).... Wide seasonal variations in plasma concentration of this compound are found in the male flounder, whereas it is present only in trace amounts in the plasma of the female flounder throughout the year....
Glucose-6-phosphate dehydrogenase: the key to sex-related xenobiotic toxicity in hepatocytes of european flounder (platichthys flesus l.)?... The strongly decreased supply of NADPH in hepatocytes of females may explain the reduced and/or delayed NADPH-dependent activity of xenobiotic biotransformation systems such as cytochrome P450 (CYP450) and a lower capacity of non-enzymatic defence systems such as reduced glutathione that is particularly observed in female flounder....
Sex-specific biotransformation and detoxification after xenobiotic exposure of primary cultured hepatocytes of european flounder (platichthys flesus l.)... In hepatocytes of female flounder, biotransformation was slower and the capacity of non-enzymatic antioxidant defences and detoxification of toxic aldehydes was lower than in males....
Reduced nicotinamide adenine dinucleotide phosphate and the higher incidence of pollution-induced liver cancer in female flounder... For example, female flounder have a threefold higher incidence of macroscopic liver nodules than males of the same age class in polluted environments of the North Sea that progress toward ...
