Dictionnaire français - anglais

fasudil

santé / chimie - iate.europa.eu
L'invention concerne une nouvelle utilisation, dans le traitement de la sclérose latérale amyotrophique (ALS), d'un inhibiteur de la kinase Rho connu, le fasudil ou un dérivé du fasudil sélectionné parmi l'hydroxy-fasudil ou le diméthylfasudil,.

The invention relates to a new use of a known Rho kinase inhibitor, fasudil or a fasudil derivative selected from hydroy-fasudil or dimethylfasudil, in the treatment of amyotrophic lateral sclerosis (ALS).

santé - wipo.int
L'invention concerne des préparations orales à libération prolongée, contenant au moins un principe actif choisi dans le groupe constitué du chlorhydrate de fasudil et de son hydrate.

Sustained release oral preparations containing at least one active ingredient selected from the group consisting of fasudil hydrochloride and its hydrate.

santé - wipo.int
De plus, l’utilisation de fasudil dans la fabrication de médicaments pour prévenir et/ou traiter des maladies associées à des dommages et/ou à la mort des neurones.

Moreover, the use of fasudil in manufacturing medicants for preventing and/or treating diseases related to damages and/or death of neuron.

santé - wipo.int
L'invention concerne une utilisation d'une formulation pharmaceutique contenant une 1-(5-isoquinolinesulfonyl)homopipérazine (FASUDIL) et des dérivés de ce composé dans un corps matriciel et une enveloppe entourant ce corps matriciel.

The invention relates to the use of a pharmaceutical formulation comprising 1-(5-isoquinolinesulfonyl)homopiperazine (FASUDIL) and derivatives thereof in a matrix body and an envelope surrounding the matrix body.

santé - wipo.int
L’utilisation du fasudil dans la présente invention comprend l’utilisation dans la fabrication de médicaments pour induire la régénération de cellules souches neurales de cerveau adulte et/ou la protection des fonctions neurologiques.

The use of fasudil in the present invention includes the use in manufacturing medicants for inducing the regeneration of adult brain neural stem cells and /or protecting the neurological functions.

santé - wipo.int
Exposure to the rock inhibitor fasudil promotes gliogenesis of neural stem cells in vitroFasudil is a clinically approved Rho-associated protein kinase (ROCK) inhibitor that has been used widely to treat cerebral consequences of subarachnoid hemorrhage....
santé - core.ac.uk - PDF: core.ac.uk

Publications scientifiques

Fasudil inhibits proliferation and migration of hep-2 laryngeal carcinoma cells... Fasudil, a selective Rho-kinase inhibitor, is found to exert antitumor effects on several types of cancer, but whether fasudil has antitumor effects on laryngeal carcinoma is ...
général - core.ac.uk - PDF: doaj.org
Fasudil delays onset, and ameliorates severity of eae.... Fasudil was injected (i.p.)...
général - core.ac.uk - PDF: figshare.com
High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial katp channelsAbstract Background The current study was carried out to determine whether fasudil hydrochloride (fasudil), a Rho-kinase inhibitor, has myocardial postconditioning (PostC) activity under hyperglycemia as well as normoglycemia, and if so, whether the ...
général - core.ac.uk - PDF: doaj.org
Effect of fasudil on rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats Effect of fasudil on Rho-kinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats.BackgroundAlthough...
général - core.ac.uk -


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