Disclosed herein are methods and compositions for promoting endochondral bone formation.

What is the Difference Between Endochondral Ossification and Intramembranous Ossification?

What is the Similarity Between Endochondral Ossification and Intramembranous Ossification?

On the other hand most of the bones in the body are formed from endochondral ossification.

What is the difference between Intramembranous ossification and endochondral ossification?

Most bones in the human skeleton are made through endochondral ossification.

Endochondral ossification begins with points in the cartilage called “primary ossification centers.

Endochondral ossification begins with points in the cartilage called "primary ossification centers.

The long bones of the limbs develop from cartilage through a process known as endochondral ossification.

Modulating this endochondral phenotype may be an attractive approach to engineering the osseous phase of an osteochondral implant.

A particulate bone of defined sizes which has a unique property of direct bone osteoinduction without going through endochondral ossification stage is disclosed.

The invention includes methods of promoting endochondral bone formation by down-regulating the expression of the DIO2 gene or the activity of the deiodinase protein.

The formation of bone during the fetal stage of development occurs by two processes: Intramembranous ossification and endochondral ossification.

The formation of bone during the fetal stage of development occurs by two processes: intramembranous ossification and endochondral ossification.

The long bones of the limbs develop from cartilage through a process known as endochondral ossification.