Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs...pig.Results: Draflazine, dipyridamole, dilazep, lidoflazine, soluflazine, and KF24345 showed efficacy in the CFA thermal hyperalgesia model....
Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. implications for its future role in cardioprotection....0.5, 1, 2, 4, and 6 mg draflazine (a selective nucleoside transport inhibitor) on hemodynamic and neurohumoral parameters and ex vivo nucleoside transport inhibition....
Population analysis of the non linear red blood cell partitioning and the concentration-effect relationship of draflazine following various infusion ratesAims To investigate the impact of the specific red blood cell binding on the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine after i.v....
Studies of the nucleoside transporter inhibitor, draflazine, in the human myocardium.... The aim of the present study was to determine the effect of the nucleoside transporter inhibitor, draflazine, on the force of contraction in human myocardium and the affinity of the compound for the nucleoside transporter....
