Systems useful for carrying out the method include tripartite constructs including a DNA-binding domain, a ligand binding domain, and an activation domain.
The biosensor molecule produces a signal from the signal domain upon binding of the analyte by the analyte binding domain.
The first chimeric gene comprises a DNA-binding domain that recognizes a binding site on the detectable gene in the host cell and a first RNA-binding domain.
The present invention relates to a gene delivery vehicle comprising a general nucleic acid binding domain and an integrin binding domain.
The invention also provides a zinc-binding domain and a dimerisation domain of Siah.
A solved three-dimensional crystal structure of a human PXR ligand binding domain polypeptide is disclosed, along with a crystal form of the PXR ligand binding domain.
The domain with a binding function may comprise a receptor binding domain, and the domain with an effector function may have enzymatic activity, in particular protease inhibitor activity.
Diphtheria toxin polypeptides comprising a mutant R binding domain exhibit reduced target cell binding and may be used as vaccines to immunize a mammal against infection by Corynebacterium diphtheria.
The second chimeric gene comprises a transcriptional activation domain and a second RNA-binding domain.
Peptides comprising the La autoantigen binding domain (LAP) are disclosed.
The magnetic recording layer has a magnetization inversion domain, a first magnetization fixation domain and a second magnetization fixation domain.
Both the first magnetization fixation domain and the second magnetization fixation domain are connected to the same one end of the magnetization inversion domain.
The first magnetization fixation domain and second magnetization fixation domain have first fixation magnetization and second fixation magnetization in fixed direction, respectively.
The DNA construct may further encode a mannose binding domain.
Interaction between both the first RNA-binding domain and the hybrid RNA and the second RNA-binding domain and the hybrid RNA in the host cell causes expression of the detectable gene.
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