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didésoxyadénosine

DDA

santé - iate.europa.eu

didésoxyadénosine

dideoxyadenosine

santé - iate.europa.eu

On traite l'hépatite B par l'administration d'une quantité efficace de 2',3'-didésoxyguanosine, 2',3'-didésoxyadénosine, ou 2',3'-didésoxyinosine.

Hepatitis B is treated by administering an effective amount of 2',3'-dideoxyguanosine, 2',3'-dideoxyadenosine, or 2',3'-dideoxyinosine.

santé - wipo.int

L'invention se rapporte à des procédés de synthèse de 2',3'-didésoxycytidine, 2',3'-didésoxyguanosine, 2',3'-didésoxyadénosine, 2',3'-didésoxyinosine et 2',3'-didésoxyguanosine, et de 3'-O-benzoyl-2'-désoxyribonucléoside.

Methods for synthesis of 2',3'-dideoxycytidine, 2',3'-dideoxyguanosine, 2',3'-dideoxyadenosine, 2',3'-dideoxyinosine and 2',3'-dideoxyguanosine, and 3'-O-benzoyl-2'-deoxyribonucleoside.

chimie - wipo.int

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Kinetics and mechanism of dna repair. preparation, purification and some properties of caged dideoxynucleoside triphosphates.Caged dideoxyribosylthymine triphosphate, dideoxyadenosine triphosphate and arabinosylcytosine triphosphate were prepared in high yield by reaction with 1-(2-nitrophenyl)diazoethane at pH 4 and room temperature for 24...

général - core.ac.uk - PDF: www.pubmedcentral.nih.gov

Conversion of 2′,3′-dideoxyadenosine (dda) and 2′,3′-didehydro-2′,3′-dideoxyadenosine (d4a) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis b virus Abstract2′,3′-Dideoxyadenosine (ddA), 2′,3′-didehydro-2′,3′-dideoxyadenosine (d4A) and their lipophilic 5′-monophosphate triester (aryloxyphosphoramidate) prodrugs were evaluated for their ...

Enhanced inhibition of the edhf phenomenon by a phenyl methoxyalaninyl phosphoramidate derivative of dideoxyadenosine... In the present study, we show that a lipophilic phosphoramidate pronucleotide derivative of dideoxyadenosine, 2′,3′-ddA-PMAPh, exhibits enhanced activity as an inhibitor of EDHF-type smooth muscle hyperpolarizations induced by acetylcholine (ACh) compared to the parent...

PDF: www.pubmedcentral.nih.gov

Termination of deoxyribonucleic acid in escherichia coli by 2′,3′-dideoxyadenosine2′,3′-Dideoxyadenosine was previously shown to be lethal to Escherichia coli and to inhibit deoxyribonucleic acid (DNA) synthesis irreversibly in this organism....

PDF: www.pubmedcentral.nih.gov

The enzymatic termination of polydeoxynucleotides by 2′,3′-dideoxyadenosine triphosphateThe nucleoside 2′,3′-dideoxyadenosine is lethal to E....

PDF: www.pubmedcentral.nih.gov

Publications scientifiques

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The secreted lipoprotein, mpt83, of mycobacterium tuberculosis is recognized during human tuberculosis and stimulates protective immunity in mice... We assessed the immunogenicity and protective efficacy of MPT83 as a protein vaccine, with monophosphyl lipid A (MPLA) in dimethyl-dioctadecyl ammonium bromide (DDA) as adjuvant, or as a DNA vaccine in C57BL/6 mice and mapped the T cell epitopes with peptide scanning....

santé / activité agricole / production - core.ac.uk - PDF: citeseerx.ist.psu.edu

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Sirna delivery with chitosan: influence of chitosanmolecular weight, degree of deacetylation, and amine to phosphateratio on in vitro silencing efficiency, hemocompatibility, biodistribution,and in vivo efficacy...systems.For understanding which parameters produce effective delivery, a libraryof precisely characterized chitosans was produced at different degreesof deacetylation (DDAs) and average molecular weights (Mn)....

santé - core.ac.uk - PDF: figshare.com

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Memory cd4+ t cells are protective early, but not late, after mtb challenge.... CD45 binding in the lung 4wpi in mice vaccinated with DDA-MPL ESAT63-17 (left) or unvaccinated (right)....

santé - core.ac.uk - PDF: figshare.com

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Predictive value of respiratory symptoms and bronchial hyperresponsiveness to diagnose asthma in new zealand ... The prevalence of current doctor diagnosed asthma (DDA) defined as asthma confirmed by a physician and an asthma attack in the last 12 months was 8.3%....

santé - core.ac.uk -

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Effect of incorporating cholesterol into dda:tdb liposomal adjuvants on bilayer properties, biodistribution, and immune responses... In this study, the aim was to investigate the role of cholesterol in cationic liposomal adjuvant system based on dimethyldioctadecylammonium (DDA) and trehalose 6,6'-dibehenate (TDB) which has been shown as a strong adjuvant system for vaccines against a wide range of diseases....

santé / production - core.ac.uk - PDF: core.ac.uk