Z1 in general formula (1) is represented in general formula (2).

A = n⋅d/λ ---- (1), where (2)

In some embodiments, the 3-substituted vinylboronates have the general Formula I: (see formula) with the variables in the formula being as defined in the specification.

In formula (III), R is H. In the formula M2S (VI), M represents K, Na, NH4 and in the formula M'2SO3 (VII), M' represents K, Na, NH4, MG/2, Ca/2, Ba/2.

Substituting formula in formula leads for diesel fueled vehicles to

Az1 in general formula (1) and Az2 in general formula (2) are azine rings; and Cz in general formula (1) and HAr in general formula (2) are nitrogen-containing heterocyclic rings.

Xa represents a substituent in formula (a) or formula (b).

In the above-mentioned formula, z0(x) fulfils the formula (1). (In formula (1), each of C2k's respectively corresponding to k = 1-8 represents a predetermined constant value).

The chemical formula of Tanshinone IIA was showed as follow.

Substituting formula in formula leads for petrol fueled vehicles to

The vinyl group in the formula (3) and the epoxy group in the formula (4) each is bonded in the α-position or β-position in the formula.)

Structural formula (I) Structural formula (II) Structural formula (III) Structural formula (IV) Structural formula (V) Structural formula (VI) In structural formula (III), Gluc represents glucuronic acid.

In formula (2) R1, R2, R3, and R4 are the same as in formula (1).

This invention provides compounds of Formula I or a pharmaceutically acceptable salt thereof, wherein G1, Q, D, and G2 are as defined above for Formula I. Compounds of Formula I, or a pharmaceutically acceptable salt thereof, are inhibitors of MMP-13.

In general formula (IA) and general formula (IB), * represents a bond.